Multimodal observation of live fibroblasts cells. Quantitative phase images at (a) the beginning and (b) the end of the measurement, showing the temporal evolution of the cell morphology. (c) Corresponding Raman image, where the red channel is the 2865 cm −1 band corresponding to lipids, and the green channel is the 2973 cm −1 band, corresponding to C-H stretching. Scale bars are 10 μm. The full evolution of cell morphology during the Raman scan is shown in the Additional file 1.